Lots of people are having the same issue. You can follow up here:
viewtopic.php?f=267&t=8189
Hopefully folks will come up with a crowd sourced fix. Iocaine works on the retail client and I only support retail servers. The fact that it worked on a private server before was coincidental. I cannot support multiple clients natively.

On Monday, August 15 we will be performing proactive maintenance on your MySQL server from 7:00 AM to 3:00 PM PDT. During this maintenance window we anticipate approximately 30 minutes of intermittent connectivity disruptions to that MySQL service. All other DreamHost services will remain unaffected.

Thanks very much for your patience. We greatly appreciate it!

This will show up as connection issues in Iocaine.

I saddens me to say, I'm going to have to discontinue Iocaine services starting 3/31/24. My hosting service that takes care of the Iocaine back end is discontinuing support for Python based back end and that's what I used to write all of the Iocaine stuff. I definitely do not have time to rewrite it with something else. So unless someone with the right skill set volunteers to help switch everything over, I'm going to have to shut it down.

Supporting Iocaine has been a great experience and I'll always be appreciative of the community here. All the best!